Synthesis of Varacin, a Cytotoxic Naturally Occurring Benzopentathiepin Isolated from a Marine Ascidian

DOI: 10.1021/jo00069a006

Source and publish data:

Journal of Organic Chemistry p. 4522 - 4523 (1993)

Update date:2022-08-03

Topics: Cytotoxic Naturally occurring Isolated

Authors:

Ford, Paul W.

Davidson, Bradley S.

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Article abstract of DOI:10.1021/jo00069a006

The total synthesis of varacin (1), a cytotoxic metabolite isolated from a marine ascidian, has been accomplished in 11 steps from vanillin, providing unambiguous confirmation of the unique dopamine-related benzopentathiepin structure.

Full text of DOI:10.1021/jo00069a006

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