A Highly Stereoselective Glycosylation of 2-(Phenylselenenyl)-2,3-dideoxyribose Derivative with Thymine: Synthesis of 3'-Deoxy-2',3'-didehydrothymidine and 3'-Deoxythymidine

DOI: 10.1021/jo00292a006

Source and publish data:

Journal of Organic Chemistry p. 1418 - 1420 (1990)

Update date:2022-09-26

Topics:

Authors:

Chu, Chung K.

Babu, J. Ramesh

Beach, J. Warren

Ahn, Soon K.

Huang, Haoqiang

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00292a006

A highly stereoselective synthesis of 3'-deoxy-2',3'-didehydrothymidine (D4T) and 3'-deoxythymidine (D2T) was achieved from the condensation of 2-(phenylselenenyl)-2,3-dideoxyribose derivative and silylated thymine in the presence of trimethylsilyl triflate.

Full text of DOI:10.1021/jo00292a006

Products guided by the article

Product name:1-O-acetyl-5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-2-(phenylselenenyl)-D-erythro-pentafuranose

Cas No:149656-26-8

R&D Labs maybe for 149656-26-8

SuZhou Bichal Biological Technology CO.,LTD

Contact:+86-512-68051130

Address:NO.32 huoju road HI-TECH Industrial development zone SuZhou China
ZK Biochem Group Co., Ltd

Contact:+86-532-80762375

Address:No. 6, Hongkong Middle Road, Qingdao, China
Huayang chemical Co., LTD

Contact:+86-18653358619

Address:zibo
Hangzhou Sartort Biopharma Co., Ltd

website:http://www.sartort.com

Contact:86-571-87039693

Address:No. 57, Tech Park Road, Hangzhou, Zhejiang, China
Zhengzhou Xinlian Chemical Tech Co. ,Ltd

Contact:0371-65771781 021-52042910

Address:H Part, Building I, No. 700 Gonglu Road, Pudong New Area, Shanghai

Relevant to this article

Rational design, synthesis, and crystallographic analysis of a hydroxyethylene-based HIV-1 protease inhibitor containing a heterocyclic P₁'-P₂' amide bond isostere

Doi:10.1021/jm00045a015
(1994)
Bismuth trichloride–mediated cleavage of phenolic methoxymethyl ethers

Doi:10.1080/00397911.2016.1158270
(2016)
Doi:10.1002/hlca.193702001208
()
Convergent Approaches to the Vitamin D Skeleton Using a Transition Metal Catalyzed Carbometalation/Capture Strategy

Doi:10.1016/S0040-4039(00)93384-7
(1993)
Doi:10.1021/jo00795a008
(1972)
On the reactions of the carbapenem, meropenem, in the soluble fraction of the rat kidney

Doi:10.3109/00498259409043231
(1994)

Article Doi