Chemical and Pharmaceutical Bulletin p. 430 - 433 (1999)
Update date:2022-08-04
Topics:
Okada, Hiroshi
Kato, Masanari
Koyanagi, Tohru
Mizuno, Kazuhiko
Water-soluble benzoylphenylurea derivatives were synthesized as candidate prodrugs and their antitumor activities were examined in vivo against P388 leukemia. Some of the prodrugs were highly soluble in water and showed good antitumor activities against P388 leukemia cells in mice when injected intravenously.
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