
Tetrahedron Letters p. 3621 - 3624 (1993)
Update date:2022-08-02
Topics:
Soloshonok, Vadim A.
Kirilenko, Alexander G.
Kukhar', Valery P.
Resnati, Giuseppe
The base-catalyzed isomerization of N-benzylimines (or enamines) of β-polyfluoroalkyl-β-ketocarboxylic esters cleanly affords the N-benzylidene derivatives of β-polyfluoro-β-aminocarboxylic esters which are hydrolyzed to corresponding amino acids in high overall yields.
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Doi:10.1016/S0040-4039(00)60527-0
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