Synthetic Communications p. 2027 - 2039 (1993)
Update date:2022-08-03
Topics:
Kerdesky
Haight
Narayanan
Nordeen
Scarpetti
Seif
Wittenberger
Morton
A new and efficient synthesis of A-81988, an angiotensin II antagonist, is described. The preparation utilizes a novel method for tetrazole formation from nitriles requiring trimethylsilyl azide and a catalytic amount of dialkyltin oxide.
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