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An application of the evans-prasad 1,3-syn diol synthesis to a stereospecific synthesis of the C10-C27 segment of rapamycin

DOI: 10.1016/S0040-4039(00)60598-1

Source and publish data:

Tetrahedron Letters p. 3993 - 3996 (1993)

Update date:2022-09-26

Topics:

Authors:

Horvath, Raymond F.Horvath, Raymond F.

Linde II, Robert G.Linde II, Robert G.

Hayward, Cheryl M.Hayward, Cheryl M.

Joglar, JesusJoglar, Jesus

Yohannes, DanielYohannes, Daniel

Danishefsky, Samuel J.Danishefsky, Samuel J.

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Article abstract of DOI:10.1016/S0040-4039(00)60598-1

An efficient regioselective and stereoselective approach to the C10-C27 fragment of rapamycin is described.

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Full text of DOI:10.1016/S0040-4039(00)60598-1

Products guided by the article

Product name:(E)-(2R,5S)-10-Benzenesulfonyl-5-benzyloxy-2,8-dimethyl-7-oxo-dec-8-enoic acid ethyl ester

Cas No:150988-47-9

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