Extracyclic Stereocontrolled Alkylation of (1R,5S)-4-Ethyl-6,6-dimethyl-3-(phenylsulfonyl)bicyclohept-3-en-2-one. A Highly Stereocontrolled Synthesis of (-)-Kanshone A

DOI: 10.1021/jo00071a025

Source and publish data:

Journal of Organic Chemistry p. 5145 - 5152 (1993)

Update date:2022-09-26

Topics: Synthesis Alkylation Stereocontrolled

Authors:

Kato, Michiharu

Watanabe, Masataka

Awen, Bahlul, Z.

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Article abstract of DOI:10.1021/jo00071a025

(1R,5S)-4-Ethyl-6,6-dimethyl-3-(phenylsulfonyl)bicyclo<3.1.1>hept-3-en-2-one (7) was prepared from (+)-nopinone (1) in six steps and 70percent overall yield via (1R,5R)-6,6-dimethyl-3-(phenylthio)bicyclo<3.1.1>hept-3-en-2-one (2).Alkylation reactions of 7

Full text of DOI:10.1021/jo00071a025

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Product name:(1R,3R,4S,5R)-4-Ethyl-6,6-dimethyl-3-(phenylthio)bicyclo<3.1.1>heptan-2-one

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