Synthesis and antiviral activity of 2'-substituted 9-[2- (phosphonomethoxy)ethyl]guanine analogues

DOI: 10.1021/jm00071a003

Source and publish data:

Journal of Medicinal Chemistry p. 2726 - 2738 (1993)

Update date:2022-08-04

Topics:

Authors:

Bronson Bronson

Yang Yang

Patick Patick

Alam Alam

Brankovan

Datema Datema

Hitchcock

Martin Martin

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Article abstract of DOI:10.1021/jm00071a003

A series of 2'-substituted derivatives of 9-[2- (phosphonomethoxy)ethyl]guanine (PMEG, 1) have been synthesized and evaluated in vitro for anti-human immunodeficiency virus (HIV) activity in the XTT assay and for anti-herpes activity in the plaque reducti

Full text of DOI:10.1021/jm00071a003

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