Synthesis and antiviral activity of 2'-substituted 9-[2- (phosphonomethoxy)ethyl]guanine analogues

DOI: 10.1021/jm00071a003

Source and publish data:

Journal of Medicinal Chemistry p. 2726 - 2738 (1993)

Update date:2022-08-04

Topics:

Authors:

Bronson Bronson

Yang Yang

Patick Patick

Alam Alam

Brankovan

Datema Datema

Hitchcock

Martin Martin

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00071a003

A series of 2'-substituted derivatives of 9-[2- (phosphonomethoxy)ethyl]guanine (PMEG, 1) have been synthesized and evaluated in vitro for anti-human immunodeficiency virus (HIV) activity in the XTT assay and for anti-herpes activity in the plaque reducti

Full text of DOI:10.1021/jm00071a003

Products guided by the article

Product name:(R)-3-azido-1-O-benzyl-2-O-<(diisopropylphosphono)methyl>-1,2-propanediol

Cas No:151223-07-3

R&D Labs maybe for 151223-07-3

Melone Pharmaceutical Co., ltd

Contact:+86-411 82593920, 82593631

Address:No 232, JInma Roda, Development Zone, Dalian, China
Innua Petrochem Ltd.

Contact:+1-284-4950244

Address:Box 3069, Road Town, Tortola, British Virgin Islands
Suzhou ATL Chemical Co.,ltd

Contact:+86-0512-69209969

Address:Room 317,Lushan Road,Suzhou New District,Jiangsu Province,China.
Shandong Dayi Chemical Co., Ltd.

website:http://www.dayi.com.cn

Contact:+86- 535-7388728. 15306386031

Address:No 1 Danya west road, Laiyang City, Shandong province
ANHUI CHEM-BRIGHT BIOENGINEERING CO.,LTD

Contact:86-561-4080321

Address:No.8 Lieshan Industrial Zone of Huaibei

Relevant to this article

Neutral and cationic group 4 metal compounds containing octamethyldibenzotetraazaannulene (Me₈taa^2-) ligands. Synthesis and reactivity of (Me₈taa)MX₂ and (Me₈taa)MX⁺ complexes (M = Zr, Hf;

Doi:10.1021/om970814x
(1998)
Synthesis of 5-methyl-5-deaza nonclassical antifolates as inhibitors of dihydrofolate reductases and as potential antipneumocystis, antitoxoplasma, and antitumor agents

Doi:10.1021/jm00074a026
(1993)
Doi:10.1016/S0008-6215(00)81672-9
(1967)
Investigating the microwave-accelerated Claisen rearrangement of allyl aryl ethers: Scope of the catalysts, solvents, temperatures, and substrates

Doi:10.1016/j.tetlet.2020.151995
(2020)
Rh(III)-Catalyzed C-H amidation with N-Hydroxycarbamates: A new entry to N-Carbamate-protected arylamines

Doi:10.1021/ol403477w
(2014)
Definitive Synthesis of Methyl α-kedarosaminide, a Sugar Component of the Antitumor Antibiotic Kedarcidin

Doi:10.1016/S0040-4039(00)60622-6
(1993)

Article Doi