Stereoselective Bromination of Dehydroamino Acids with Controllable Retention or Inversion of Olefin Configuration

Article abstract of DOI:10.1021/jo00068a047

Dehydroamino acids react with brominating reagents to produce syn-α-bromo imines as the major products, which undergo tautomerization to mixtures of the diastereomeric (E)- and (Z)-β-bromo-α,β-dehydroamino acids upon treatment with base.Herein, we examine