Journal of Fluorine Chemistry p. 137 - 142 (1994)
Update date:2022-08-03
Topics:
Driss, C.
Chaabouni, M. M.
Baklouti, A.
O-Alkylation of 1-F-alkyl-2-fluoroethanols may be achieved at 25-40 deg C by the action of halogenated derivatives in a basic medium and in the presence of a phase-transfer catalyst.This reaction is followed in most cases by dehydrofluorination to yield polyfluorinated vinyl acetals when the alkylating agent is dichloromethane and F-alkylated vinyl ethers when it is a monohalogenated derivative.With some other alkylating agents (iodomethane, 3-bromocyclohexene, 1-bromo-3-methylbut-2-ene and 1-bromobut-2-ene), partial or no dehydrofluorination is achieved in the homogeneous phase by the action of KOH in triethylene glycol at 100 deg C.
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