Studies of the synthesis, immunology, and cytotoxicity of a cyclic octapeptide corresponding to TNF-alpha-(59-66).

DOI: 10.1021/jm00078a020

Source and publish data:

Journal of medicinal chemistry p. 4302 - 4307 (1993)

Update date:2022-08-03

Topics:

Authors:

Sheh Sheh

Lin Lin

Jeng Jeng

Chen Chen

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Article abstract of DOI:10.1021/jm00078a020

In an attempt to investigate possible binding domains of the tumor necrosis factors (TNF), we have previously synthesized a cyclic hexapeptide corresponding to murine TNF-(127-132) (cTNF-1). In this report, we describe the synthesis and biological activit

Full text of DOI:10.1021/jm00078a020

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