Synthesis of restrictinol and 9,10,11,12-tetrahydro-7- desmethylrestricticin

DOI: 10.1248/cpb.41.1191

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1191 - 1193 (1993)

Update date:2022-08-03

Topics:

Authors:

Tsukuda Tsukuda

Umeda Umeda

Masubuchi

Shirai Shirai

Shimma Shimma

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Article abstract of DOI:10.1248/cpb.41.1191

Restrictinol 2 and 9,10,11,12-tetrahydro-7-desmethylrestricticin (Ro 09- 1571) have been synthesized from L-glucose. Ro 09-1571 showed improved in vitro antifungal activity and chemical stability as compared with Restricticin 1.

Full text of DOI:10.1248/cpb.41.1191

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