Synthesis of structural analogs of leukotriene B4 and their receptor binding activity

DOI: 10.1021/jm00074a012

Source and publish data:

Journal of Medicinal Chemistry p. 3308 - 3320 (1993)

Update date:2022-07-29

Topics:

Authors:

Kingsbury

Pendrak Pendrak

Leber Leber

Boehm Boehm

Mallet Mallet

Sarau Sarau

Foley Foley

Schmidt Schmidt

Daines Daines

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Article abstract of DOI:10.1021/jm00074a012

Structural analogs of leukotriene B₄ (LTB₄) were designed using a preferred conformation of LTB₄ (1). Appending an aromatic ring scaffold between LTB₄ carbons 7 and 11 led to quinoline analogs 3 and 15. A simila

Full text of DOI:10.1021/jm00074a012

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