A NEW SYNTHESIS 2-ACYL-1,2,3,6,7,11b-HEXAHYDROPYRAZINOISOQUINOLIN-4-ONES BASED ON N-CYANOMETHYL DERIVATIVES OF 2-PHENYL-ETHYLAMIDES OF ACYLGLYCINES

DOI: 10.1007/BF00531659

Source and publish data:

Chemistry of Heterocyclic Compounds p. 170 - 173 (1993)

Update date:2022-08-05

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Authors:

Shekhter, O. V.

Kuklenkova, O. B.

Sergovskaya, N. L.

Tsizin, Yu. S.

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Article abstract of DOI:10.1007/BF00531659

A new route for the synthesis of 2-acyl-1,2,3,6,7,11b-hexahydropyrazino<2,1-a>isoquinolin-4-ones has been studied which includes a stage in which substituted piperazinones are obtained by reductive cyclization of N-cyanomethyl derivatives of 2-phenylethylamides of acylglycines under influence of Raney alloy in formic acid.

Full text of DOI:10.1007/BF00531659

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