A NEW SYNTHESIS 2-ACYL-1,2,3,6,7,11b-HEXAHYDROPYRAZINOISOQUINOLIN-4-ONES BASED ON N-CYANOMETHYL DERIVATIVES OF 2-PHENYL-ETHYLAMIDES OF ACYLGLYCINES

DOI: 10.1007/BF00531659

Source and publish data:

Chemistry of Heterocyclic Compounds p. 170 - 173 (1993)

Update date:2022-08-05

Topics:

Authors:

Shekhter, O. V.

Kuklenkova, O. B.

Sergovskaya, N. L.

Tsizin, Yu. S.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1007/BF00531659

A new route for the synthesis of 2-acyl-1,2,3,6,7,11b-hexahydropyrazino<2,1-a>isoquinolin-4-ones has been studied which includes a stage in which substituted piperazinones are obtained by reductive cyclization of N-cyanomethyl derivatives of 2-phenylethylamides of acylglycines under influence of Raney alloy in formic acid.

Full text of DOI:10.1007/BF00531659

Products guided by the article

Product name:N-(2-phenylethyl)-N-(cyanomethyl)amide of hippuric acid

Cas No:152189-68-9

R&D Labs maybe for 152189-68-9

Chuzhou Baiao Biologhy S&T Co., Ltd.

Contact:+86-25-83212599；+86-25-83212699 13705185959

Address:Room 905, Tianzheng International Platza, No.399, Zhongyang Road ,Nanjing, Jiangsu Province, China
Chengdu NoVi Biotechnology Co., Ltd.(expird)

Contact:13551243286/028-81458053

Address:NO.168-1-224 JULONG ROAD WUHOU DISTRICT, CHENGDU CITY,SICHUAN PROVINCE
Shanghai Surseechem Co.,Ltd.

Contact:+86-21-61318535

Address:Building 29,No.2139 Xizha Road, Fengxian District, Shanghai
Baicao Pharmaceutical Co., Ltd.

website:http://www.jxbaicao.com

Contact:+86-796-8113329

Address:It (country) economic and technological development zone of the jinggang mountains
Beijing Apis Biotechnology Co., Ltd.

Contact:86-010-67856775-8551

Address:NO.4PUHUANGYU ROAD,FENTAI DISTRICT, BEIJING, CHINA

Relevant to this article

Chemistry and Structure of Ganefromycin

Doi:10.1021/jo00076a016
(1993)
Construction of highly substituted pyrazole derivatives with P-C bond: Access to racemic and enantioselective forms by conjugate addition of diarylphosphane oxides to α,β-unsaturated pyrazolones

Doi:10.1016/j.tet.2013.11.038
(2014)
Synthesis of the monodeoxy derivatives of 2-(trimethylsilyl)ethyl β-lactoside

Doi:10.1016/0008-6215(93)84028-5
(1993)
Antitumor agents. 148. Synthesis and biological evaluation of novel 4 beta-amino derivatives of etoposide with better pharmacological profiles.

Doi:10.1021/jm00030a003
(1994)
Synthesis, pharmacological evaluation, and σ₁ receptor interaction analysis of hydroxyethyl substituted piperazines

Doi:10.1021/jm401707t
(2014)
Synthesis of (1R,4R,7S)- and (1S,4S,7S)-2-(4-tolylsulfonyl)5-phenylmethyl-7-methyl-2,5-diazabicyclo [2.2.1]heptanes via regioselective opening of 3,4-epoxy-D-proline with lithium dimethyl cuprate

Doi:10.1002/jhet.5570300241
(1993)

Article Doi