Synthesis of (1R,4R,7S)- and (1S,4S,7S)-2-(4-tolylsulfonyl)5-phenylmethyl-7-methyl-2,5-diazabicyclo [2.2.1]heptanes via regioselective opening of 3,4-epoxy-D-proline with lithium dimethyl cuprate

DOI: 10.1002/jhet.5570300241

Source and publish data:

Journal of Heterocyclic Chemistry p. 517 - 523 (1993)

Update date:2022-08-05

Topics:

Authors:

Remuzon Remuzon

Bouzard Bouzard

Clemencin

Dussy Dussy

Essiz Essiz

Jacquet Jacquet

Saint-Germain

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jhet.5570300241

Full text of DOI:10.1002/jhet.5570300241

Products guided by the article

Product name:ethyl (2R,3R,4S)-1-(4-tolylsulfonyl)-3-methyl-4-hydroxy-2-hydroxymethylpyrrolidine

Cas No:152955-42-5

R&D Labs maybe for 152955-42-5

Jinzhou Jiutai Pharmaceutical Co.,Ltd

Contact:+86-0416-5179890

Address:No.41, Taianli, Taihe District, Jinzhou, Liaoning
Laohekou Jinghong Chemical Co.,Ltd

Contact:+86-0710-3702747

Address:163.East，Huagong Road，Laohekou
Shijiazhuang City Xiehe Pharmaceutical Co., Ltd

Contact:+86-311-80817929

Address:Shangzhuang,Shijiazhuang,China
Taizhou Green Peptide Trading Co., Ltd.

Contact:13736652831

Address:Room 1501, No71, Yuehe Road, Taizhou City, Zhejiang Province, China
Xiamen Goodhealth Pharmchem Co., Ltd.

Contact:0086-592-2097683

Address:404R No.2 54# Minzu Rd., Xiamen, China

Relevant to this article

Discovery of KDM5A inhibitors: Homology modeling, virtual screening and structure-activity relationship analysis

Doi:10.1016/j.bmcl.2016.03.048
(2016)
The synthesis and biological characteristics of new orally active cephems

Doi:10.7164/antibiotics.46.1897
(1993)
Inhibition of MMP-1 and MMP-13 with phosphinic acids that exploit binding in the S₂ pocket

Doi:10.1016/S0960-894X(98)00729-X
(1999)
Oxidative Verknuepfung von Phosphinomethanidliganden and Titanocen- und Bismutzentren: selektive C-C-, P-C- und P-P-Bindungsbildung

Doi:10.1016/0022-328X(93)86060-U
(1993)
α-Aryl pyrrolidine sulfonamides as TRPA1 antagonists

Doi:10.1016/j.bmcl.2015.11.088
(2016)
Discovery of (10 R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17- tetrahydro- 2H -8,4-(metheno)pyrazolo[4,3- h ][2,5,11]- benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a macrocyclic inhibitor of anaplastic lymphoma kinase (ALK) and c-ros oncogene 1 (ROS1) with preclinical brain exposure and broad-spectrum potency against ALK-resistant mutations

Doi:10.1021/jm500261q
(2014)

Article Doi