Synthesis of Thiazoloisoindoles by Intramolecualar Cycloaddition-Elimination Reactions of 4-Methyl-5-(substituted)imino-Δ2-1,2,3,4-thiatriazolines

DOI: 10.1016/S0040-4020(01)85758-6

Source and publish data:

Tetrahedron p. 4439 - 4446 (1993)

Update date:2022-08-02

Topics:

Authors:

L'abbe, Gerrit

Leurs, Stefan

Sannen, Ingrid

Dehaen, Wim

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)85758-6

Fused thiazolidine 11 and thiazoline derivatives 19a-c are obtained by intramolecular cycloaddition-elimination reactions of appropriately substituted 5-iminothiatriazolines 10 and 18a-c.The incorporation of a sidechain phenyl group excercises a favorable effect on cyclization since no reaction is observed with 25.Comparable intermolecular reactions also fail to occur.

Full text of DOI:10.1016/S0040-4020(01)85758-6

Products guided by the article

Product name:o-iodobenzyl thiocyanate

Cas No:152418-10-5

R&D Labs maybe for 152418-10-5

Radiant Pharma & Tech Company

Contact:+86-511-88790000

Address:338 North Yushan Rd, Zhenjiang, Jiangsu 212016
HENAN NEW BLUE CHEMICAL CO.,LTD

website:http://www.newbluechem.com

Contact:86-371-55170693/55170694

Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China
Shanghai Yuantai Chemical Products Co., Ltd

Contact:021--66129803

Address:Chengyin Road,Shanghai,China
Nanjing Qirui Material Co., Ltd.

Contact:+86-25-52320053

Address:F4-5, #17 Building, Chuang Yi Yuan, No.6 Guanghua East Street, Nanjing, 210007 P.R.China
Chengda Pharmaceuticals Co., Ltd.

Contact:+86-573-84601188

Address:hengshan Road 5# in Jiashan, zhejiang

Relevant to this article

Inhibition of carbonic anhydrases from the extremophilic bacteria Sulfurihydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1, 3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties

Doi:10.1016/j.bmc.2013.11.042
(2014)
Design, synthesis, anticancer activity, and solid lipid nanoparticle formulation of indole-and benzimidazole-based compounds as pro-apoptotic agents targeting bcl-2 protein

Doi:10.3390/ph14020113
(2021)
A Synthesis of (-)-Denopamine

Doi:10.1016/S0957-4166(00)80062-2
(1993)
Reaction of phosphonium ylides with 4-triphenylmethyl-1,2-benzoquinone

Doi:10.1016/S0040-4020(01)96274-X
(1993)
Facile synthesis of optically pure 1,2-diaryl (and 1-alkyl-2-aryl) ethyl and propylamines

Doi:10.1021/ol027464h
(2003)
Synthesis and nucleophilic aromatic substitution of 3-fluoro-5-nitro-1-(pentafluorosulfanyl)benzene

Doi:10.3762/bjoc.12.21
(2016)

Article Doi