Synthesis of Thiazoloisoindoles by Intramolecualar Cycloaddition-Elimination Reactions of 4-Methyl-5-(substituted)imino-Δ2-1,2,3,4-thiatriazolines

DOI: 10.1016/S0040-4020(01)85758-6

Source and publish data:

Tetrahedron p. 4439 - 4446 (1993)

Update date:2022-08-02

Topics:

Authors:

L'abbe, Gerrit

Leurs, Stefan

Sannen, Ingrid

Dehaen, Wim

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Article abstract of DOI:10.1016/S0040-4020(01)85758-6

Fused thiazolidine 11 and thiazoline derivatives 19a-c are obtained by intramolecular cycloaddition-elimination reactions of appropriately substituted 5-iminothiatriazolines 10 and 18a-c.The incorporation of a sidechain phenyl group excercises a favorable effect on cyclization since no reaction is observed with 25.Comparable intermolecular reactions also fail to occur.

Full text of DOI:10.1016/S0040-4020(01)85758-6

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