Synthesis of Thiazoloisoindoles by Intramolecualar Cycloaddition-Elimination Reactions of 4-Methyl-5-(substituted)imino-Δ2-1,2,3,4-thiatriazolines

DOI: 10.1016/S0040-4020(01)85758-6

Source and publish data:

Tetrahedron p. 4439 - 4446 (1993)

Update date:2022-08-02

Topics:

Authors:

L'abbe, Gerrit

Leurs, Stefan

Sannen, Ingrid

Dehaen, Wim

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)85758-6

Fused thiazolidine 11 and thiazoline derivatives 19a-c are obtained by intramolecular cycloaddition-elimination reactions of appropriately substituted 5-iminothiatriazolines 10 and 18a-c.The incorporation of a sidechain phenyl group excercises a favorable effect on cyclization since no reaction is observed with 25.Comparable intermolecular reactions also fail to occur.

Full text of DOI:10.1016/S0040-4020(01)85758-6

Products guided by the article

Product name:o-iodobenzyl thiocyanate

Cas No:152418-10-5

R&D Labs maybe for 152418-10-5

BAODING SINO-CHEM INDUSTRY CO.,LTD

Contact:0312-5956088

Address:NO.8 FUXING ROAD,CHINA
Zhonghao (dalian) Research and Design Institute of Chemical Industry Co., Ltd

Contact:+86 411 84674606

Address:201, Huangpu Road , Shahekou District, Dalian ,116023-China
Suns Chemical Sdn Bhd

Contact:0086 371 65711996

Address:Jalan 4/3, Kawasan Perindustrian Serendah, 48000 Rawang,
Hangzhou Zyter Biological & Chemical Technology Co., Ltd.

website:http://www.zyterpharm.com

Contact:+86-18858184290

Address:West Wenyi Road, Cangqian, Yuhang
Sichuan Sangao Biochemical Co., Ltd

Contact:+86-28-84874233

Address:19F, Bldg.2, Shudu Center, Tianfu 2nd St., Hi-tech zone, Chengdu 610041, Sichuan Province, China.

Relevant to this article

Inhibition of carbonic anhydrases from the extremophilic bacteria Sulfurihydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1, 3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties

Doi:10.1016/j.bmc.2013.11.042
(2014)
Design, synthesis, anticancer activity, and solid lipid nanoparticle formulation of indole-and benzimidazole-based compounds as pro-apoptotic agents targeting bcl-2 protein

Doi:10.3390/ph14020113
(2021)
A Synthesis of (-)-Denopamine

Doi:10.1016/S0957-4166(00)80062-2
(1993)
Reaction of phosphonium ylides with 4-triphenylmethyl-1,2-benzoquinone

Doi:10.1016/S0040-4020(01)96274-X
(1993)
Facile synthesis of optically pure 1,2-diaryl (and 1-alkyl-2-aryl) ethyl and propylamines

Doi:10.1021/ol027464h
(2003)
Synthesis and nucleophilic aromatic substitution of 3-fluoro-5-nitro-1-(pentafluorosulfanyl)benzene

Doi:10.3762/bjoc.12.21
(2016)

Article Doi