Design, Synthesis, and Biological Activity of Methoctramine-Related Tetraamines Bearing an 11-Acetyl-5,11-dihydro-6H-pyridobenzodiazepin-6-one Moiety:Structural Requirements for Optimum Occupancy of Muscarine Receptor Subtypes As Revealed by S

DOI: 10.1021/jm00046a021

Source and publish data:

Journal of Medicinal Chemistry p. 3363 - 3372 (1994)

Update date:2022-08-03

Topics:

Authors:

Minarini, Anna

Bolognesi, Maria L.

Budriesi, Roberta

Canossa, Marco

Chiarini, Alberto

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00046a021

Tetraamines 5-13 and diamines 14-17 as well as monoamine 18 were synthesized, and their biological profiles at muscarinic receptor subtypes were assessed by functional experiments in isolated guinea pig left atrium (M₂) and ileum (M₃

Full text of DOI:10.1021/jm00046a021

Products guided by the article

Product name:1,24-bis<<(5,11-dihydro-6-oxo-6H-pyrido<2,3-b><1,4>benzodiazepin-11-yl)carbonyl>methyl>-8,17-dimethyl-1,8,17,24-tetraazatetracosane

Cas No:152429-63-5

R&D Labs maybe for 152429-63-5

Naturalin Bio-Resource Co., Ltd

website:http://www.naturalin.com

Contact:+86-0731-84430651

Address:B1-402, Lu-Valley Enterprise Square.No.27 Wenxuan Road. Lu-Valley Hi-Tech District.
Zouping Fuhai Technology Development Co., Ltd.

Contact:+0532-86934525 18660293207

Address:jiuhu town industrial park Zouping County,bingzhou Provincejiuhu town industrial park
Hopechem Co., Ltd.

Contact:+86-20-38011066

Address:3510, Diwang Commercial Center, 5002 Shennan Rd, Shenzhen, P.R.China
Fuxin Jintelai Fluorin Chemical Co., Ltd.

Contact:+86-0418-8229599

Address:, 7th Huagong Road, Fluorine industry development zone (Yimatu Town,Fumeng County),Fuxin City, Liaoning Province, China
Anhui Charm Imp.&Exp.Co., Ltd

website:http://www.chinacharm.cn/

Contact:86 551 5316260

Address:No. 211,XiangZhang Road,Hefei City,Anhui Province,China

Relevant to this article

Synthesis of 4-unsubstituted dihydropyrimidines having acyl and alkoxycarbonyl groups at 5- and 6-positions by cyclization-elimination reactions using 1,3-diaza-1,3-butadienes

Doi:10.1016/j.tetlet.2013.11.038
(2014)
Synthesis of Kdo-α-glycosides of lipid A derivatives

Doi:10.1016/0008-6215(93)84029-6
(1993)
Manganese(III) acetate and copper(II) acetate promoted oxidation of β- enaminoamides and β-enaminoesters

Doi:10.1016/S0040-4020(99)00286-0
(1999)
Synthetic utility of 4'-nitrobenzenesulfenanilide in the functionalization of carbon-carbon double and triple bonds: Its use in the bromosulfenylation of alkenes and alkynes

Doi:10.1016/S0040-4020(01)82386-3
(1993)
Stereocontrolled synthesis of all-syn 3,4-disubstituted l-prolines: Studies of the reductive rearrangement of unactivated tertiary allylic alcohols

Doi:10.1016/j.tet.2013.11.040
(2014)
Stereoselective Synthesis of 1-Aryl-4a-methyloctahydrophenanthrenes via Cyclization Reactions Initiated by Benzylic Cations

Doi:10.1021/jo00079a045
(1993)

Article Doi