Nonprostanoid prostacyclin mimetics. 4. Derivatives of 2-[3-[2-(4,5- diphenyl-2-oxazolyl)ethyl]phenoxy]acetic acid substituted α to the oxazole ring

Article abstract of DOI:10.1021/jm00076a017

The 4,5-diphenyloxazole derivatives 2-4 were previously identified as nonprostanoid prostacyclin (PGI₂) mimetics. A series of derivatives of 2-4 bearing substitutents at the carbon atom α to the oxazole ring were synthesized and evaluated as in