Nonprostanoid prostacyclin mimetics. 4. Derivatives of 2-[3-[2-(4,5- diphenyl-2-oxazolyl)ethyl]phenoxy]acetic acid substituted α to the oxazole ring

DOI: 10.1021/jm00076a017

Source and publish data:

Journal of Medicinal Chemistry p. 3871 - 3883 (1993)

Update date:2022-08-03

Topics:

Authors:

Meanwell

Rosenfeld

Wright Wright

Brassard

Buchanan

Federici

Fleming Fleming

Gamberdella

Hartl Hartl

Zavoico Zavoico

Seiler Seiler

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Article abstract of DOI:10.1021/jm00076a017

The 4,5-diphenyloxazole derivatives 2-4 were previously identified as nonprostanoid prostacyclin (PGI₂) mimetics. A series of derivatives of 2-4 bearing substitutents at the carbon atom α to the oxazole ring were synthesized and evaluated as in

Full text of DOI:10.1021/jm00076a017

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