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Synthesis of 2,4-Disubstituted Thiazoles and Selenazoles as Potential Antifilarial and Antitumor Agents. 2. 2-Arylamido and 2-Alkylamido Derivatives of 2-Amino-4-(isothiocyanatomethyl)thiazole and 2-Amino-4-(isothiocyanatomethyl)selenazole

DOI: 10.1021/jm00076a013

Source and publish data:

Journal of Medicinal Chemistry p. 3849 - 3852 (1993)

Update date:2022-07-29

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Authors:

Kumar, YatendraKumar, Yatendra

Green, RachelGreen, Rachel

Wise, Dean S.Wise, Dean S.

Wotring, Linda L.Wotring, Linda L.

Townsend, Leroy B.Townsend, Leroy B.

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Article abstract of DOI:10.1021/jm00076a013

The synthesis of a series of 2-arylamido and 2-alkylamido derivatives of 2-amino-4-(isothiocyanatomethyl)thiazole and 2-amino-4-(isothiocyanatomethyl)selenazole is described.In vitro antiproliferative evaluations were carried out using L1210 cells.The 2-(

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Full text of DOI:10.1021/jm00076a013

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Product name:2-benzamido-4-(isothiocyanatomethyl)thiazole

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