Enzymatic resolution of acylates of prochiral phenolic 1-aryl- and 1-arylalkyl-1,2,3,4-tetrahydroisoquinolinols, which possess a Guaiacol-type moiety, by use of immobilized lipase in organic solvent

DOI: 10.1016/S0957-4166(00)80135-4

Source and publish data:

Tetrahedron Asymmetry p. 933 - 942 (1993)

Update date:2022-08-04

Topics:

Authors:

Hoshino Hoshino

Tanahashi

Okada Okada

Akita Akita

Oishi Oishi

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Article abstract of DOI:10.1016/S0957-4166(00)80135-4

Enzymatic resolution of acylates of prochiral phenolic 1-aryl, and 1-arylalkyl-1,2,3,4-tetrahydroisoquinolinols, which possess a guaiacol-type moiety by use of lipase immobilized with celite in water-saturated organic solvent gave the corresponding acylates and phenols in moderate optical yields.

Full text of DOI:10.1016/S0957-4166(00)80135-4

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Product name:Acetic acid 1-(3,4-dimethoxy-phenyl)-7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-6-yl ester

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