Synthesis of novel modified dipeptide inhibitors of human collagenase: β- Mercapto carboxylic acid derivatives

Article abstract of DOI:10.1021/jm00077a006

The synthesis of a series of thiol-containing, modified dipeptide inhibitors (8) of human collagenase, which incorporate various carboxylic acid derivatives at the presumed P₁ position, β to the thiol group, is described. The compounds were eva