The Synthesis of Novel Mimics of the Sialyl Lewis X Determinant

DOI: 10.1016/S0957-4166(00)86284-9

Source and publish data:

Tetrahedron Asymmetry p. 2061 - 2076 (1994)

Update date:2022-08-05

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Authors:

Allanson, Nigel M.

Davidson, Alan H.

Floyd, Christopher D.

Martin, Fionna M.

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Article abstract of DOI:10.1016/S0957-4166(00)86284-9

Disaccharide mimics of the sialyl Lewis X (sLe^x) ligands have been prepared as potential antagonists of binding to the lectin domains of the E-selectin adhesion molecule.Versatile derivatives of sialic acid provide an entry to a series of simpl

Full text of DOI:10.1016/S0957-4166(00)86284-9

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