Synthesis of Oligonucleotides Containing Site-Specific Carcinogen Adducts. Preparation of the 2-Cyanoethyl N,N-Diisopropylphosphoramidite of N-(2'-Doexyguanosin-8-yl)-2-(acetylamino)fluorene with Fmoc as the Base-Protecting Group

DOI: 10.1021/jo00082a011

Source and publish data:

Journal of Organic Chemistry p. 556 - 563 (1994)

Update date:2022-08-03

Topics:

Authors:

Zhou, Yuanzhong

Chladek, Stanislav

Romano, Louis J.

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Article abstract of DOI:10.1021/jo00082a011

A 9-fluorenylmethoxycarbonyl (Fmoc) group was used to protect the exocyclic amine on the modified guanine of N-(2'-deoxyguanosin-8-yl)-2-(acetylamino)fluorene (dG-C8-AAF) so that oligonucleotides containing a site-specific AAF adduct could be prepared.Rea

Full text of DOI:10.1021/jo00082a011

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