Total syntheses of strychnan- and aspidospermatan-type alkaloids. 2. Generation of 15-(3-furanyl) ABCE tetracyclic intermediates

Article abstract of DOI:10.1021/jo00078a029

The synthesis of N^b-benzyl-2-(dimethyl 2-malonyl)- and 2-(methyl 2- acetyl)tryptamines (21, 25) provides access to methyl 4-(3-furanyl)- 1,2,3,4,5,6-hexahydroazepino[4,5-b]indole-5-carboxylate (12) and methyl 3- benzyl-5-(3-furanyl)-2,3,3a,4,5,