Synthesis and application of triazole derivatives. Synthesis of 3- and 5- acyl-1,2,4-triazoles via lithiation of 1-alkyl-1H-1,2,4-triazoles

DOI: 10.1248/cpb.41.1226

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1226 - 1231 (1993)

Update date:2022-08-04

Topics:

Authors:

Ohta Ohta

Kawasaki

Fukuno Fukuno

Yamashita

Tada Tada

Kawabata

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Article abstract of DOI:10.1248/cpb.41.1226

N-Unsubstituted 3-acyl-1H-1,2,4-triazoles (3), and 5-acyl-1-alkyl-1H- 1,2,4-triazoles (4) were synthesized by acylation of 5-lithiotriazoles with amides. The 3-position of l-methyl-5-phenylthio-1H-1,2,4-triazole (11) was lithiated by lithium 2,2,6,6-tetra

Full text of DOI:10.1248/cpb.41.1226

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