Direct synthesis of 3-fluoro-α-fluoromethyl-p-tyrosine

Article abstract of DOI:10.1016/S0022-1139(00)80476-5

3-Fluoro-α-fluoromethyl-p-tyrosine was synthesized directly by the reaction of acetyl hypofluorite with α-fluoromethyl-p-tyrosine. α-Fluoromethyl-p-tyrosine was prepared by a four-step reaction while acetyl hypofluorite was prepared from elemental fluorin