A total synthesis of 2'-deoxy-9-deazaguanosine (9-deaza-dG) and its incorporation into triple helix forming oligodeoxyribonucleotides with antiparallel motif

Article abstract of DOI:10.1016/S0040-4039(00)61681-7

A simple synthesis of 2-amino-7-(2-deoxy-β-D-erythro-pentofuranosyl)pyrrolo-[3,2-d]pyrimidi n-4(3H)-one (9-deaza-dG) has been achieved and it has been incorporated into triplex forming oligonucleotides using the solid-support, phosphoramidite chemistry. 9