The synthesis of a C9-C17 fragment of discodermolide

DOI: 10.1016/S0040-4039(00)61480-6

Source and publish data:

Tetrahedron Letters p. 8163 - 8166 (1993)

Update date:2022-09-26

Topics:

Authors:

Evans Evans

Golec Golec

Gillespie

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)61480-6

The asymmetric synthesis of a synthetically useful fragment corresponding to the C₉-C₁₇ region of the immunosuppressant lactone discodermolide is reported. The route incorporates the use of an unsaturated lactone to provide a trisubstituted olefin with absolute control of geometry.

Full text of DOI:10.1016/S0040-4039(00)61480-6

Products guided by the article

Product name:(2R,4S,5R,6R)-1-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-7-benzyloxy-5-hydroxy-2,4,6-trimethyl-heptane-1,3-dione

Cas No:153628-57-0

R&D Labs maybe for 153628-57-0

ANTAI BIO-TECH CO LTD

website:http://www.antaibio.com

Contact:0086-21-65663057

Address:Room 2108, Building 2，No. 489 Zhengli Road，200433
Huzhou City Linghu Xinwang Chemical Co.,Ltd.

Contact:86-572-3948695/3945236

Address:huzhou
Linyi Shengxin Pharmaceutical R&D Co., Ltd

Contact:+86-18653953873

Address:West First of Yufeng Road, Yishui County
QINGDAO TAOSIGN INTERNATIONAL TRADE CO.,LIMITED

Contact:+86-0532-82683616

Address:RM1402, Doublestar Seacoase 7#, No. 5 Guizhou Road, Qingdao, Shandong, China
LianYunGang Chiral Chemical(CHINA) CO.,LTD

Contact:+86-518-83616958 +86-519-82884848

Address:LianYunGang Chemical Industry Park (JiangSu)

Relevant to this article

Structural modulation of silver complexes and their distinctive catalytic properties

Doi:10.1039/c3dt52655k
(2014)
Hydrogen bonded supra-molecular framework in inorganic-organic hybrid compounds of Mn(II) and Zn(II): Syntheses, structures, and photoluminescent studies

Doi:10.1016/j.molstruc.2013.11.026
(2014)
Is an acyl group at O-3 in glucosyl donors able to control α-stereoselectivity of glycosylation? the role of conformational mobility and the protecting group at O-6

Doi:10.1016/j.carres.2013.11.016
(2014)
Synthesis of 3,3-difluoro-DL-alanine and 3,3-difluoro-DL-alanine precursors

Doi:10.1055/s-1993-25979
(1993)
Tridentate Lewis-acids based on triphenylsilane

Doi:10.1039/c6dt04293g
(2017)
K-region oxides and imines of benzo[b]phenanthro[2,3-d]thiophene and benzo[b]phenanthro[3,2-d]thiophene

Doi:10.1002/jhet.5570300611
(1993)

Article Doi