Synthesis of 3,3-difluoro-DL-alanine and 3,3-difluoro-DL-alanine precursors

DOI: 10.1055/s-1993-25979

Source and publish data:

Synthesis p. 961 - 963 (1993)

Update date:2022-09-26

Topics: Synthesis Reaction Precursors DL-alanine: Authors:

D'Orchymont

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Article abstract of DOI:10.1055/s-1993-25979

The key intermediate to 3,3-difluoroalanine, 2,2-difluoro-1-ethylthioethylamine hydrobromide (2), was prepared by the Steglich and Weygand procedure. Its conversion to N-benzyloxycarbonyl-2,2-difluoro-1-ethenylethylamine (5) followed by oxidation and subsequent deprotection of the amine afforded the 3,3-difluoroalanine.

Full text of DOI:10.1055/s-1993-25979

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Article Doi

Synthesis of 3,3-difluoro-DL-alanine and 3,3-difluoro-DL-alanine precursors

DOI: 10.1055/s-1993-25979

Source and publish data:

Authors:

Article abstract of DOI:10.1055/s-1993-25979

Full text of DOI:10.1055/s-1993-25979

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