α-Isocyanatoacrylonitriles from alkylidene- or arylidenecyanoacetic acids; synthesis and reactions

DOI: 10.1055/s-1994-25405

Source and publish data:

Synthesis p. 56 - 60 (1994)

Update date:2022-08-02

Topics:

Authors:

Jaafar Jaafar

Francis Francis

Danion-Bougot

Danion Danion

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Article abstract of DOI:10.1055/s-1994-25405

The Curtius reaction converts alkylidene- or arylidenecyanoacetic acids to α-isocyanatoacrylonitriles in a stereospecific way. These versatile intermediates allow an easy access to arylacetic acids and various amino acid derivatives, as well as β-lactams or 2-azabutadienes.

Full text of DOI:10.1055/s-1994-25405

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