Journal of Heterocyclic Chemistry p. 1431 - 1436 (1993)
Update date:2022-08-05
Topics:
Dong Chin Kim
Won Hyung Yoon
Choi
Kim
A study directed toward the synthesis of saulatine (5,8,9,14a-tetrahydro- 3,4,11,12-tetramethoxy-isoquino[1,2-b]benzazepine-6,14-dione) is described. The successful synthetic route consists of three steps starting with 3,4- dimethoxyphenethylamine and 2-bromo-(3,4-dimethoxy-2- ethoxycarbomethylphenyl)-acetate. It was found that the methoxy moieties present on the aromatic rings prohibit the use of the intramolecular Friedel- Crafts reaction with a Lewis acid catalyst for ring construction because of their demethylation tendency under the reaction conditions.
View Morewebsite:http://www.uvchemkeys.com
Contact:0086-021-58785816
Address:RM2607 Building No.1 Guosheng, Lane 388, Zhongjiang Road, Putuo District, Shanghai 200062 China
Chengdu Yunyi International Trade Co., Ltd
Contact:0411-39894967
Address:china
Hangzhou GreenCo Science & Technology Co., Ltd.
Contact:86-571-88257303
Address:1713 Room,Jingui Building,Gudun Road,Xihu District,Hangzhou,China
Cerametek Materials（ShenZhen）Co., Ltd.
Contact:+86-755-2324.2554
Address:A3-#9, YongChuan Street, Suite 501
Contact:86-29-88665278
Address:Exhibition International Building , Chang'an Road , Xi'an , 710000 ,China
Doi:10.1166/jnn.2017.14076
(2017)Doi:10.1016/S0040-4020(01)81551-9
(1993)Doi:10.1016/S0277-5387(03)00132-3
(2003)Doi:10.1002/hlca.19670500602
(1967)Doi:10.1002/hlca.19930760809
(1993)Doi:10.1055/s-1994-25517
(1994)
