New deoxynojirimycin derivatives as potent inhibitors of intestinal α-glucohydrolases

DOI: 10.1016/S0960-894X(97)00012-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 355 - 360 (1997)

Update date:2022-09-26

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Authors:

Lesur, Brigitte

Ducep, Jean-Bernard

Lalloz, Marie-Noelle

Ehrhard, Anne

Danzin, Charles

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Article abstract of DOI:10.1016/S0960-894X(97)00012-7

New N-alkyl, alkenyl and benzyl substituted DNJ derivatives incorporating a silicon atom in the substituent were synthesised. Kinetic parameters (K(i), t( 1/4 )) for inhibition of rat intestinal α-glucohydrolases as well as human lysosomal α-glucosidases

Full text of DOI:10.1016/S0960-894X(97)00012-7

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