An efficient synthesis of the dolabellanes

Article abstract of DOI:10.1016/S0040-4039(00)61504-6

Eleven-membered carbocycles have been prepared by the intramolecular condensations of α-sulfonyl carbanions with α,β-unsaturated aldehydes. Desulfonylation provides an efficient stereocontrolled synthesis of allylic alcohols featuring the [9.3.0] cyclotetradecane skeleton which characterized the dolabellane diterpenes.