Improved synthesis of trifluoromethyl sulfones used as intermediates for the preparation of di- or tri-substituted olefins

Article abstract of DOI:10.1016/0022-1139(93)02909-X

Primary and secondary trifluoromethyl sulfones (triflones) are efficiently obtained from easily available sodium trifluoromethanesulfinate (triflinate) and alkyl bromides in N,N-dimethylacetamide.This technique is more powerful than the potassium triflinate/acetonitrile system.Ethyl aconitate can be also produced in one step from ethyl bromoacetate and diisopropylethylamine, sodium triflinate being a catalyst.