SYNTHESIS OF OLIGONUCLEOTIDES VIA PHOSPHORAMIDITE APPROACH UTILIZING 2-DIPHENYLMETHYLSILYLETYHYL (DPSE) AS A PHOSPHORUS PROTECTING GROUP

DOI: 10.1016/S0040-4020(01)85503-4

Source and publish data:

Tetrahedron p. 9255 - 9266 (1994)

Update date:2022-08-04

Topics:

Authors:

Ravikumar, Vasulinga T.

Wyrzykiewicz, Tadeusz K.

Cole, Douglas L.

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Article abstract of DOI:10.1016/S0040-4020(01)85503-4

2-Diphenylmethylsilylethyl (DPSE) is a new protecting group for internucleotidic bonds in the synthesis of oligodeoxyribonucleotides by the phosphoramidite approach.This group is stable to acidic conditions and can be removed under mild β-fragmentation co

Full text of DOI:10.1016/S0040-4020(01)85503-4

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