
Tetrahedron p. 10531 - 10554 (1993)
Update date:2022-08-02
Topics:
Okamura, Hiroaki
Kuroda, Satoru
Ikegami, Satoru
Tomita, Kenji
Sugimoto, Yu-ichi
et al.
This paper describes the enantioselective synthesis of key fragments (12,18,24, and 35) for the synthesis of aplysiatoxin (1a), a potent cancer promoter, and their convergent assembly to Kishi's aldehyde (2).Since 2 has already been transformed into 1a in
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Doi:10.1021/ol400051n
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(1994)