Stereocontrolled synthesis of pyrimidine 2',3'-dideoxy-β-nucleosides by intramolecular glycosylation

Article abstract of DOI:10.1016/S0040-4039(00)73186-8

β-2',3'-Dideoxynucleosides and their 3'-azido and 3'-fluoro substituted derivatives were synthesized in a stereocontrolled manner by the dimethyl(methylthio)sulfonium tetrafluoroborate promoted intramolecular glycosylation of phenyl 2,3-dideoxy-5-O-(2-pyrimidyl)-1-thioglycosides followed by hydrolysis or ammonolysis.