Chemistry of Heterocyclic Compounds p. 1077 - 1086 (1993)
Update date:2022-07-30
Topics:
Shutalev, A. D.
Komarova, E. N.
Pagaev, M. T.
Ignatova, L. A.
Dehydration of 4-hydroxyhexahydropyrimidine-2-thiones formed 1,2,3,6-tetrahydropyrimidine-2-thiones containing no substituent at the C(4) carbon atom.It is shown that the synthesized compounds, in contrast to their 4-alkyl-substituted analogs, react easily with various nucleophilic reactants (alcohols,butylmercaptan, benzenesulfinic acid, hydrazoic acid, p-toluidine) to from the corresponding 4-functionally substituted hexahydropyrimidine-2-thiones.
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