Tetrahedron p. 9721 - 9734 (1993)
Update date:2022-08-03
Topics:
Saito, Kenji
Yamamoto, Makoto
Yamada, Kazutoshi
Tagaki, Hideo
A highly diastereoselective one-pot tandem Michael-Michael addition reaction developed in a rotamerically locked conformation is described.Reaction of isocyanates 8 - 13 with hydroxylactone 14 gave tandem Michael-Michael adducts 22 - 26 in good to excelle
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