Synthesis of cerpegin

DOI: 10.1248/cpb.42.715

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 715 - 717 (1994)

Update date:2022-08-03

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Authors:

Matsuo Matsuo

Arase Arase

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Article abstract of DOI:10.1248/cpb.42.715

Cerpegin (1), a new pyridone alkaloid, was synthesized starting from the Michael reaction of phenylthioacetonitrile (2) and 2-methoxycarbonyl-4,4- dimethyl-2-buten-4-olide (3) in five steps. Catalytic hydrogenation of a nitrile group in the presence of a

Full text of DOI:10.1248/cpb.42.715

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