Solid phase synthesis of α-hydroxyglycine extended peptides -biological precursors of peptide amides

Article abstract of DOI:10.1016/S0040-4039(00)75818-7

Fmoc α-methoxyglycine can be incorporated into solid phase peptide synthesis (SPPS) methodology to give α-hydroxyglycine extended peptides on final deprotection and cleavage from the solid support with trifluoroacetic acid containing 5% H₂O.