Photocontrolled uptake and release of photochromic haptens by monoclonal antibodies. Evidence of photoisomerization inside the hapten-binding site

Article abstract of DOI:10.1246/bcsj.67.1380

Monoclonal antibodies against a tetrapeptide carrying a photochromic azobenzene moiety (Glu-azoAla-Gly-Gly, azoAla = L-p-phenylazophenylalanine) were prepared under conditions where the azobenzene moiety was in the trans form. The binding of the hapten pe