Tetrahedron Letters p. 3309 - 3312 (1994)
Update date:2022-08-03
Topics:
Agami, Claude
Couty, Francois
Lequesne, Christelle
Diastereoisomerically pure N-Boc 2-acyloxazolidines were synthesized from phenylglyoxal and ethyl glyoxylate.Reaction of these heterocycles with Grignard reagents is highly stereoselective.Homochiral 1,2-diols were ultimately obtained after N-deprotection, hydrolysis and reduction of the intermediate α-hydroxy aldehyde.The asymmetric induction can be explained by a chelated model.
View MoreContact:+86-22-83718541
Address:32th Floor, Rongqiao Center Intersection of Changjiang Road and Nankai Six Road Nankai District Tianjin 300102, China
Jewim Pharmaceutical (Shandong) Co., Ltd
Contact:+8615621883869
Address:山东省泰安市高新技术产业开发区配天门大街西首
Cerametek Materials（ShenZhen）Co., Ltd.
Contact:+86-755-2324.2554
Address:A3-#9, YongChuan Street, Suite 501
Shanghai Xinda Pharmaceuticals Co., Ltd.
Contact:86-21-33692333-8008
Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China
Beijing Harmony Chemical Co., Ltd.
Contact:86-010-84956928
Address:Room 207, Jin feng he B building, No 8 Xin Jie Kou Wai Street, Xi Cheng District, Beijing,PRC. 10008
Doi:10.1016/S0040-4020(01)85643-X
(1994)Doi:10.1021/jo00087a054
(1994)Doi:10.1039/c39940000831
(1994)Doi:10.1016/S0040-4039(00)73051-6
(1994)Doi:10.1002/chem.200902172
(2009)Doi:10.1134/S1070363214010095
()
