Tetrahedron Letters p. 3309 - 3312 (1994)
Update date:2022-08-03
Topics:
Agami, Claude
Couty, Francois
Lequesne, Christelle
Diastereoisomerically pure N-Boc 2-acyloxazolidines were synthesized from phenylglyoxal and ethyl glyoxylate.Reaction of these heterocycles with Grignard reagents is highly stereoselective.Homochiral 1,2-diols were ultimately obtained after N-deprotection, hydrolysis and reduction of the intermediate α-hydroxy aldehyde.The asymmetric induction can be explained by a chelated model.
View MoreZhenjiang Haitong Chemical Industry Co., Ltd.
Contact:+86 (511) 8448-0369
Address:Baoyan Town, Dantu District, Zhenjiang City, Jiangsu, China
website:http://www.tbbmed.com
Contact:86--21-50498136
Address:Room 6002, Building 7-1, No.160 Basheng Road,Pudong Area,Shanghai China
Contact:+86-574-89075960
Address:#100 Xiang Yun Road, New High tech area, Ningbo, China
Zhejiang Haizhou Pharmaceutical Co., Ltd.
website:https://www.haizhoupharma.com/
Contact:+86-576-88221016
Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
Contact:86-571-61063068
Address:LINAN
Doi:10.1016/S0040-4020(01)85643-X
(1994)Doi:10.1021/jo00087a054
(1994)Doi:10.1039/c39940000831
(1994)Doi:10.1016/S0040-4039(00)73051-6
(1994)Doi:10.1002/chem.200902172
(2009)Doi:10.1134/S1070363214010095
()
