Tetrahedron Letters p. 2087 - 2090 (1994)
Update date:2022-09-26
Topics:
Anderson, James C.
Ley, Steven V.
Marsden, Stephen P.
A convergent synthesis of the C22 - C32 portion of rapamycin has been achieved by way of a Nozaki-Kishi coupling of vinyl iodide 14 with aldehyde 13. This aldehyde is available by the stereoselective addition of organometallic reagen
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