Studies towards the total synthesis of rapamycin: A convergent and stereoselective synthesis of the C22-C32 carbon framework

DOI: 10.1016/S0040-4039(00)73057-7

Source and publish data:

Tetrahedron Letters p. 2087 - 2090 (1994)

Update date:2022-09-26

Topics:

Authors:

Anderson, James C.

Ley, Steven V.

Marsden, Stephen P.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)73057-7

A convergent synthesis of the C₂₂ - C₃₂ portion of rapamycin has been achieved by way of a Nozaki-Kishi coupling of vinyl iodide 14 with aldehyde 13. This aldehyde is available by the stereoselective addition of organometallic reagen

Full text of DOI:10.1016/S0040-4039(00)73057-7

Products guided by the article

Product name:(3S,5R,6R)-3,5-Dimethyl-6-((R)-1-phenylselanyl-ethyl)-tetrahydro-pyran-2-one

Cas No:156474-43-0

R&D Labs maybe for 156474-43-0

Lanzhou SchiffChem Co.,Ltd

Contact:86-931-8272767

Address:Room 602, No.461, Nanchang Road, Chengguan District, Lanzhou City, China PRC
lianyungang jinkang pharmaceutical technology co., ltd.

Contact:008651885445517

Address:Jinshan industrial park, Ganyu county, Lianyungang, Jiangsu Province, 222115, China
Angelisun(Chongqing) Pharmaceutical Co., LTD.

Contact:+86-23-68030926-816

Address:D1-7 Tech & Entrepreneurs Park, Kecheng Road, Erlang Hi-Tech Areas, Chongqing, China
Shanghai SMEC Trading Co., Ltd.

website:http://www.shanghaismec.com

Contact:+86-21-68811293

Address:ROOM 1101,NO.800 SHANGCHENG RD,SHANGHAI,CHINA
Shenzhen Feiming Science and Technology Co,. Ltd

Contact:+86-755-85232577

Address:#B2309, Fenglin International Center ,Jixiang Road, Longcheng street, LongGang District, Shenzhen city, Guangdong province, China.

Relevant to this article

A formal total synthesis of salvadione

Doi:10.1002/ejoc.200600361
(2006)
Photostable BODIPY-based molecule with simultaneous type i and type II photosensitization for selective photodynamic cancer therapy

Doi:10.1039/c3tb21547d
(2014)
Synthesis of heterocyclic α-aminophosphonic acids

Doi:10.1080/00397919408011729
(1994)
Highly selective and controllable synthesis of arylhydroxylamines by the reduction of nitroarenes with an electron-withdrawing group using a new nitroreductase BaNTR1

Doi:10.1039/c3cc48590k
(2014)
N-metallacycles from [CpMX₂]₂ and alkynylpyridines: Synthesis, reaction pathway, and aromaticity

Doi:10.1021/om401154c
(2014)
The first used half sandwich ruthenium(II) complexes bearing benzimidazole moiety for N-alkylation of amines with alcohols This paper is dedicated to Professor Irina P. Beletskaya on the occasion of her contribution to catalysis.

Doi:10.1016/j.jorganchem.2014.01.007
(2014)

Article Doi