Synthetic Communications p. 2523 - 2529 (1996)
Update date:2022-07-29
Topics:
Yoshida, Masato
Suzuki, Daiki
Iyoda, Masahiko
Treatment of XCF2COOEt (X = Cl and Br) with SmI2 in THF gave efficiently β,β-difluorinated enolate equivalent, which was used for Reformatsky type reaction with aldehydes and ketones to give 2,2-difluoro-3-hydroxy ester.
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