Synthesis of C-6 pyrimidine acyclic nucleoside analogs as potential antiviral agents

Article abstract of DOI:10.1080/15257779408013263

A number of pyrimidine acyclic nucleosides in which the acyclic moiety is attached to the C-6 position rather than N-1 of the pyrimidine ring have been prepared. This was accomplished via treatment of lithiated 2,4-dimethoxy- 5,6-dimethylpyrimidine, or, 2

Full text of DOI:10.1080/15257779408013263

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Nucleosides and Nucleotides
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Synthesis of C-6 Pyrimidine Acyclic
Nucleoside Analogs as Potential Antiviral
Agents
Ling-Yih Hsu c , Dean S. Wise a b , William M. Shannon d , John C.
Drach a b & Leroy B. Townsend a b
a Department of Medicinal Chemistry, College of Pharmacy, Ann
Arbor, Michigan, 48109
b Department of Biologic and Materials Sciences, School of Dentistry,
University of Michigan, Ann Arbor, Michigan, 48109
c School of Pharmacy, National Defense Medical Center, Taipei,
Taiwan, Republic of China
d Microbiology Research Department, Southern Research Institute,
Birmingham, Alabama, 35255
Version of record first published: 23 Sep 2006.
To cite this article: Ling-Yih Hsu, Dean S. Wise, William M. Shannon, John C. Drach & Leroy B.
Townsend (1994): Synthesis of C-6 Pyrimidine Acyclic Nucleoside Analogs as Potential Antiviral Agents,
Nucleosides and Nucleotides, 13:1-3, 563-584
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