Phytochemistry p. 569 - 574 (1988)
Update date:2022-07-29
Topics:
Ikeya, Yukinobu
Taguchi, Heihachiro
Mitsuhashi, Hiroshi
Takeda, Shigefumi
Kase, Yoshio
Aburada, Masaki
A new dibenzocyclooctadiene lignan, isoschizandrin was isolated from the fruits of Schizandra chinensis.The structure was elucidated on the basis of the spectral analysis and chemical correlation with schizandrin and (+)-deoxyschizandrin.In experiments using rats, schizandrin and its derivatives, including isoschizandrin, showed inhibitory effects on stress-induced gastric ulceration (p.o).Key Word Index-Schizandra chinensis; Schizandraceae; dibenzocyclooctadiene; lignan; isoschizandrin; anti-ulcer effect.
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Doi:10.1021/ml500039g
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