Synthesis and pharmacological evaluation of verapamil analogs with restricted molecular flexibility

DOI: 10.1016/0223-5234(94)90211-9

Source and publish data:

European Journal of Medicinal Chemistry p. 139 - 148 (1994)

Update date:2022-08-05

Topics:

Authors:

Teodori, E.

Dei, S. Dei, S.

Romanelli, M. N.

Scapecchi, S.

Gualtieri, F.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0223-5234(94)90211-9

Several analogs of verapamil, which are characterized by a reduced molecular flexibility, have been synthesized.Their pharmacological activity has been evaluated on guinea-pig atria (negative chronotropic and inotropic activities) and guinea-pig aorta str

Full text of DOI:10.1016/0223-5234(94)90211-9

Products guided by the article

Product name:ethyl-2-(3,4-dimethoxyphenyl)-2-cyano-3-methylbutanoate

Cas No:156896-98-9

R&D Labs maybe for 156896-98-9

SICHUAN ZHONGBANG NEW MATERIAL CO., LTD

website:http://www.zhongbangst.com

Contact:86-830-2585019

Address:sichuan,china
Tai zhou world Pharm & Chem Co., Ltd

Contact:+86-576-85301198

Address:Rome 1001,wangjiang plaza,unti 2,jinshan east Road linhai,zhejiang,china
Zhejiang Kaili Industrial Co., Ltd

Contact:+86-571-85241926

Address:lantian business center,No.18 Moganshan Road
Beijing Mashi Fine Chemical Co.,Ltd.

Contact:+86-10-61271592

Address:Room 506, Section B, Kaichi Mansion, Industrial Development
jiangsu senxuan pharmaceutical and chemical co.,ltd

Contact:86-523-87982810

Address:hongqiao industrial zone,taixing,jiangsu china

Relevant to this article

Divergent syntheses of 2-aminonicotinonitriles and pyrazolines by copper-catalyzed cyclization of oxime ester

Doi:10.1021/ol500094w
(2014)
Gold(I)-catalyzed asymmetric aldol reactions of fluorinated benzaldehydes with an α-isocyanoacetamide

Doi:10.1016/0957-4166(94)80059-6
(1994)
Electrical Conductivity of Some Hydrazones and Binary Complexes with Transition Metals

Doi:10.1007/BF00844685
(1996)
Palladium-catalyzed formation of carbon-nitrogen bonds. Reaction intermediates and catalyst improvements in the hetero cross-coupling of aryl halides and tin amides

Doi:10.1021/ja00092a058
(1994)
Chiral non-racemic sulfoxides by asymmetric alkylation of alkanesulfenates in the presence of a chiral ammonium phase-transfer catalyst derived from Cinchona alkaloid

Doi:10.1080/17415993.2013.795226
(2013)
Synthesis of Polysubstituted 3-Methylisoquinolines through the 6π-Electron Cyclization/Elimination of 1-Azatrienes derived from 1,1-Dimethylhydrazine

Doi:10.1002/ejoc.201801076
(2018)

Article Doi