Tetrahedron Letters p. 4409 - 4412 (1994)
Update date:2022-07-31
Topics:
Couladouros, Elias A.
Soufli, Ioanna C.
Combretastatin D-2, (1), was synthesized via a 10 step sequence. Macrolactonization was performed saturated substrate 12 in high yield and the double bond was established via dehalogenation of intermediate 15.
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