An Enantioselective Approach to the Synthesis of Manzamine A

DOI: 10.1016/S0040-4039(00)73333-8

Source and publish data:

Tetrahedron Letters p. 4279 - 4282 (1994)

Update date:2022-08-05

Topics:

Authors:

Kamenecka, Theodore M.

Overman, Larry E.

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Article abstract of DOI:10.1016/S0040-4039(00)73333-8

A new approach for asymmetric construction of the pyrrolo<2,3-i>isoquinoline core of manzamine A is described.The synthesis starts with D-(-)-quinic acid and features an intermolecular Mannich reaction as the central step.

Full text of DOI:10.1016/S0040-4039(00)73333-8

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